Description. For the treatment of dogs with, or at risk from, mixed external and internal parasitic infestations. Simparica Trio is exclusively indicated when use against ticks or fleas and gastrointestinal nematodes is indicated at the same time. The veterinary medicinal product also provides concurrent efficacy for the prevention of heartworm.. Simparica Trio chewable tablets for dogs >40-60 kg 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains: Active substances: Simparica Trio chewable tablets sarolaner (mg) moxidectin (mg) pyrantel (as embonate) (mg) for dogs 1.25-2.5 kg 3 0.06 12.5 for dogs >2.5-5 kg 6 0.12 25 for dogs >5-10 kg 12 0.24 50 for dogs >10-20 kg.

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